By Robert K. Murray, David A. Bender, Kathleen M. Botham, Peter J. Kennelly, Victor W. Rodwell, P. Anthony Weil

Gain an intensive knowing of the rules of biochemistry and molecular biology as they relate to trendy medicine

Includes sixteen case histories

Clear, concise, and in complete colour, Harper’s Illustrated Biochemistry is unmatched in its skill to explain the hyperlink among biochemistry and the molecular foundation of ailment. Combining extraordinary full-color illustrations with built-in insurance of biochemical ailments and medical details, Harper’s deals a company and cautious stability of aspect and brevity now not present in the other textual content at the subject.

Following introductory chapters, the textual content is split into six major sections:
Section I addresses the constructions and features of proteins and enzymes.
Section II explains how a variety of mobile reactions make the most of or unlock power and lines the pathways during which carbohydrates and lipids are synthesized and degraded.
Section III covers the amino acids, their metabolic fates, definite beneficial properties of protein catabolism, and the biochemistry of the porphyrins and bile pigments.
Section IV describes the constitution and serve as of nucleotides and nucleic acids, DNA replication and service, RNA synthesis and amendment, protein synthesis, the rules of recombinant DNA expertise, and new realizing of the way gene expression is regulated. Section V offers with points of extracellular and intracellular conversation.
Section VI comprises fifteen particular issues, starting from nutrients, digestion and absorption to the biochemistry of aging

New to this edition:

  • New chapters on getting older, melanoma, and scientific Chemistry
  • each bankruptcy has been up-to-date to mirror the newest advances in wisdom and know-how
  • each one bankruptcy now starts with a press release of targets, by way of a short dialogue of the biomedical value of subject matters mentioned in the bankruptcy
  • 250 multiple-choice inquiries to try out your wisdom and comprehension
  • elevated variety of tables that encapsulate very important details, corresponding to diet and mineral requirements

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Harpers Illustrated Biochemistry

Achieve a radical knowing of the rules of biochemistry and molecular biology as they relate to trendy drugs contains sixteen case histories transparent, concise, and in complete colour, Harper’s Illustrated Biochemistry is unmatched in its skill to explain the hyperlink among biochemistry and the molecular foundation of illness.

Extra info for Harpers Illustrated Biochemistry

Example text

01 means that at any given moment in time, a hydrogen atom has 1 chance in 100 of being an ion and 99 chances out of 100 of being part of a water molecule. 8 × 10–9. The probability of its being part of a water molecule thus is almost unity. 8 × 109 water molecules. Hydrogen ions and hydroxide ions nevertheless contribute significantly to the properties of water. For dissociation of water, where the brackets represent molar concentrations (strictly speaking, molar activities) and K is the dissociation constant.

Botham, PhD, DSc & Peter A. Mayes, PhD, DSc 12 Biologic Oxidation Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc 13 The Respiratory Chain & Oxidative Phosphorylation Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc 14 Carbohydrates of Physiologic Significance David A. Bender, PhD & Peter A. Mayes, PhD, DSc 15 Lipids of Physiologic Significance Kathleen M. Botham, PhD, DSc & Peter A. Mayes, PhD, DSc 16 Overview of Metabolism & the Provision of Metabolic Fuels David A. Bender, PhD & Peter A.

It also minimizes energetically unfavorable contacts between water and hydrophobic groups. Hydrophobic Interactions Hydrophobic interaction refers to the tendency of nonpolar compounds to self-associate in an aqueous environment. ” Self-association minimizes the disruption of energetically favorable interactions between the surrounding water molecules. While the hydrogens of nonpolar groups such as the methylene groups of hydrocarbons do not form hydrogen bonds, they do affect the structure of the water that surrounds them.

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