By Kendall H. Lee, Penelope S. Duffy, Allan J. Bieber

Deep mind stimulation (DBS) is a time-honored remedy for flow issues corresponding to Parkinson's ailment, crucial tremor, and dystonia. Its healing good fortune has ended in the appliance of DBS for an expanding spectrum of stipulations. even though, the elemental relationships among neural activation, neurochemical transmission, and medical results in the course of DBS aren't good understood.

Drawing at the medical and examine services of the Mayo health center Neural Engineering Laboratories, this publication addresses the background of healing electric stimulation of the mind, its present software and results, and theories approximately its underlying mechanisms. It reports examine on measures of neighborhood stimulation–evoked neurochemical unencumber, imaging study on stimulation-induced neural circuitry activation, and the state-of-the-art on closed-loop suggestions units for stimulation delivery.

Show description

Read or Download Deep brain stimulation: indications and applications PDF

Similar neurosurgery books

Spinal Cord Stimulation Implantation: Percutaneous Implantation Techniques

Spinal twine stimulators (SCS) are implantable clinical units used to regard continual soreness of neurologic beginning, corresponding to sciatica, intractable again soreness, and diabetic. The gadget generates an electrical pulse close to the spinal cord's dorsal floor, offering a parasthesia sensation that alters the notion of soreness via the sufferer, and is usually utilized in conjunction with traditional scientific administration.

Photographic Atlas of Practical Anatomy II: Neck · Head · Back · Chest · Upper Extremities Companion Volume Including Nomina Anatomica and Index

Walter Thiel's excellent photos are targeted. They revolutionize macroscopic anatomy simply because - as a result of a brand new maintenance procedure constructed through the writer himself - all tissues preserve their dwelling colour, consistency and place. For the 1st time anatomical websites convey the true colour and type of human organs in addition to their real positions.

Rhinology: Diseases of the Nose, Sinuses, and Skull Base

Winner of 2013 IBPA Ben Franklin Award! This e-book offers a ravishing accomplished method of sleek rhinology administration from the leaders in a box that has considerably developed over the [last] 10 years. i'm inspired with how the ebook presents a tutorial technological know-how method of the sphere of rhinology.

Additional resources for Deep brain stimulation: indications and applications

Sample text

CRC Press, Boca Raton, FL. 45. Fins J (2003). From psychosurgery to neuromodulation and palliation: history’s lessons for the ethical conduct and regulation of neuropsychiatric research. Neurosurg Clin N Am 14, 303–319. 46. Tye SJ, Frye MA, Lee KH (2009). Disrupting disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation. Mayo Clin Proc 84, 522–532. 47. Couto MI, Monteiro A, Oliveira A, Lunet N, Massano J (2014). Depression and anxiety following deep brain stimulation in Parkinson’s disease: systematic review and meta-analysis.

Safety Considerations in Design of Stimulating Electrodes Clinical DBS electrodes consist of four or more electrode contacts, which might be configured in multiple anode/cathode configurations.

Couto MI, Monteiro A, Oliveira A, Lunet N, Massano J (2014). Depression and anxiety following deep brain stimulation in Parkinson’s disease: systematic review and meta-analysis. Acta Med Port 27, 372–382. 48. Morishita T, Fayad SM, Higuchi MA, Nestor KA, Foote KD (2014). Deep brain stimulation for treatment-resistant depression: systematic review of clinical outcomes. Neurotherapeutics 11, 475–484. 49. Kline M (1972). Mathematical Thought from Ancient to Modern Times. Oxford University Press, New York, pp.

Download PDF sample

Rated 4.14 of 5 – based on 44 votes