By Nancy C. Andreasen
Nancy Andreasen, a number one neuroscientist who's additionally Editor-in-Chief of the distinguished American magazine of Psychiatry in addition to the winner of the illustrious nationwide Medal of technology, deals right here a state of the art examine what we all know in regards to the human mind and the human genome--and exhibits how those giant branches of data are coming jointly in a boldly bold attempt to overcome psychological ailment. Scientists this day recognize extra in regards to the mind than ever prior to, due to new imaging strategies and to discoveries in neuroscience and molecular biology. Andreasen offers us a fascinating and readable description of ways all of it works, from the billions of neurons to the tiny thalamus to the ethical display screen in our prefrontal cortex. She additionally exhibits the growth made in mapping the human genome, whose 30,000 to 40,000 genes are just about all energetic within the mind. In maybe the main interesting part of the e-book, we learn gripping tales of the folks who boost psychological affliction, the chums and family members who percentage their soreness, the physicians who deal with them, and the scientists who examine them in order that larger remedies are available. This part covers 4 significant disorders--schizophrenia, manic melancholy, nervousness problems, and dementia--revealing what factors them, what occurs to the brain and mind, and the way the health problems are taken care of. ultimately, the ebook exhibits how the strong instruments of genetics and neuroscience should be mixed in the course of the subsequent a long time to construct more healthy brains and minds. Andreasen's bestselling The damaged Brain broke new flooring within the public realizing of psychological disorder. Now, by way of revealing how combining genome mapping with mind mapping can unencumber the mysteries of psychological ailment, she back bargains normal readers a remarkably clean standpoint on those devastating diseases--their nature, therapy, and attainable destiny prevention.
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Additional resources for Brave New Brain: Conquering Mental Illness in the Era of the Genome
Manifest the same condition) in comparison with nonidentical twins. This is because identical twins have almost identical genes, while nonidentical twins share only 50% of their genes. Table 3—1 shows this relationship for several common illnesses, both mental and nonmental. TABLE 3-1 Concordance Rates in Twins Type of Illness Autism Identical Twins 60% Nonidentical Twins 5% Schizophrenia, bipolar disorder, Coronary artery disease 40% 10% Depression 50% 15% Breast cancer 30% 10% 34 BROKEN BRAINS AND TROUBLED MINDS Strikingly, autism is the most "genetic" illness in the table, with a concordance rate of 60% in identical twins and 5% in nonidentical twins.
Over the years we have invented a set of false dichotomies and arbitrary categories. For creating a simple structure to assist us in analyzing and thinking, these dichotomies may be useful. But too often they have become reified, holding us back from perceiving clearly. Some of the great false dichotomies used in discussions about mental illnesses are mind and brain, drugs and psychotherapy, and genes and environment. " Mind versus Brain When another person complains of a symptom such as "feeling anxious," the first question that many people ask is: Is it "all in his mind" or is it "real"?
He also spent an hour with Jim, beginning with the comment that he had carefully reviewed the records sent over by the HMO, so he already knew quite a bit about him. "You've been having a rough time," Dr. Walker said. " By now a bit tired of his story, Jim nonetheless reviewed it again. This time he added the information about his mother's history, her response to medication, and his own thoughts about suicide. He hated to mention it, but Mary had told him that he had to. He also described how Mary had looked up DSM criteria for depression, and how he had to agree—it was 23 A WAKING NIGHTMARE a perfect match, although the match seemed to have been made in hell rather than heaven.