By David R. Brown
This ebook describes the newest learn on neurodegenerative ailment and metal-binding proteins. It lays powerful emphasis on biochemistry and mobile biology. The ailments lined within the e-book contain Parkinson's ailment, Alzheimer's illness, prion sickness, and ALS. The chapters individually learn such concerns as mechanisms of steel binding, metal-induced structural adjustments in proteins, changes in mobile steel metabolism in illness, and makes an attempt at a healing method in keeping with protein steel binding.
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Extra resources for Brain diseases and metalloproteins
7609–7616. Huang, X. , Cuajungco, M. , Atwood, C. , Hartshorn, M. , Tyndall, J. D. , Hanson, G. , Stokes, K. , Goldstein, L. , Scarpa, R. , Saunders, A. , Moir, R. , Bowden, E. , Masters, C. , Fairlie, D. , Tanzi, R. E. and Bush, A. I. indd 27 6/20/2012 11:15:27 AM 28 A Possible Key Role for Redox-Active Metal Ions and Soluble Oligomers cell-free hydrogen peroxide production and metal reduction. J. Biol. Chem. 274, pp. 37111–37116. , Riess, O. and Gasser, T. (2005) The role of α-synuclein gene multiplications in early-onset Parkinson’s disease and dementia with Lewy bodies.
T. and Klann, E. (2007) Sources and targets of reactive oxygen species in synaptic plasticity and memory. Antioxid. Redox Signal. 9, pp. 233–244. Klein, W. , Stine, W. B. and Teplow, D. B. (2004) Small assemblies of unmodified amyloid β protein are the proximate neurotoxin in Alzheimer’s disease. Neurobiol. Aging 25, pp. 569–580. Knapp, L. T. and Klann, E. (2002) Role of reactive oxygen species in hippocampal long-term potentiation: contributory or inhibitory? J. Neurosci Res. 70, pp. 1–7. Lambert, M.
2006–2010. , Ashcroft, A. , Korchazhkina, O. V. and Exley, C. (2005) Metals accelerate the formation and direct the structure of amyloid fibrils of NAC. J. Inorg. h 99, pp. 1920–1927. indd 28 6/20/2012 11:15:27 AM References 29 Kim, H. , Chae, S. , Lee, D. , Lee, S. , Park, Y. , Klein, W. , Kraﬀt, G. , and Hong, S. T. (2003) Selective neuronal degeneration induced by soluble oligomeric amyloid β protein. FASEB J. 17, pp. 118–120. Kishida, K. T. and Klann, E. (2007) Sources and targets of reactive oxygen species in synaptic plasticity and memory.