By Neville N. Osborne

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197. Falck, B. & Owman, C. (1965). A detailed methodological description of the fluorescence method for the cellular demonstration of biogenic monoamines. Acta Univ. , Sect. II, No. 7, 1-23. F. (1914). A contribution to the comparative physiology of the contractile vascular system and its regulators, the adrenalin secreting system and the sympathetic system. Phil. Trans. Roy. Soc. 205B, 153-207. F. (1919). Adrenalin in annelids. J. Physiol. 2, 73-85. M. (1973). Chemical transmission in invertebrate central nervous systems and neuromuscular junctions.

Neurobiol. 2, 231-246. J. (1973). The use of gas chromatography-mass spectrometry to measure tissue levels and turn over of acetylcholine. Adv. Biochem. Psychopharm. 7, 69-81. G. (1975). Synapses and Syntosomes. pp. 174-192. Halsted Press, New York. C. J. (1975). Mass fragmentographic determination of some acidic and alcholic metabolites of biogenic amines in the rat brain. J. Neurochem. 25, 653-658. B. J. (1966). The effect of dopa, a-methyldopa and reserpine on the dopamine content of the brain of the snail, Helix aspersa.

Biol. Med. 23, 828-837. G. L. (1964). Histochemical localization of amines in Hydra and in the sea anemone. Nature 201, 88-90. A. E. (1973). Neuromuscular junctions in the leech. J. Comp. Neurol. 151, 85-99. -C THE NEUROBIOLOGY OF A SEROTONERGIC NEURON NEVILLE N, OSBORNE Max-Planck-Institut fur experimentelle Medizin, Forschungsstelle Neurochemie, 3400 Gottingen, Germany 1. INTRODUCTION One general conclusion that can be drawn from the mass of electrophysiological and electron microscopical data which have accumulated is that there is a high degree of heterogeneity in the neurons comprising every nervous system.

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